The Science Powering Gene-On
Powered by Tricore™, the First Anti-Aging System Backed by Harvard Research to Reverse Aging at the Genetic Level.
The first formula proven to reverse skin’s biological age by reactivating sirtuins—Harvard’s newly discovered root cause of aging.


Left: Dormant sirtuins weaken cells, causing loss of structure and function.
Right: Reactivated sirtuins restore youthful shape and activity.
Sirtuin Decline:
The Root Cause of Skin Aging
For decades, aging was believed to result from surface-level damage—collagen breakdown, moisture loss, and oxidative stress. But research from Harvard Medical School, led by Professor Dr. David Sinclair, has uncovered a deeper, biological cause: the gradual decline of sirtuin activity.
Sirtuins are the master regulators of cellular repair and longevity, ensuring that key genes for collagen production, antioxidant defense, and cellular renewal stay switched on. They act as the skin’s genetic control system, delivering precise instructions to keep cells youthful, resilient, and fully functional.
However, as we age, sirtuin activity declines, and skin cells stop receiving these genetic instructions for youth. Over time, this leads to:
01
Breakdown of Genetic Repair
02
Degradation of Collagen and Elastin
03
Spread of Senescent ("Zombie") Cells
The More Sirtuin Decline, The Older Your Skin Acts
As sirtuin activity declines, cellular damage accumulates faster than the skin can repair itself, accelerating aging and leading to visible signs like wrinkles, age spots, loss of elasticity and firmness, crepiness, and thinning.
But by reactivating sirtuins, we can prevent healthy cells from aging prematurely and even restore damaged cells to a more youthful state.
Reactivate Your Sirtuins with Proprietary TriCore™ Complex
Our breakthrough TriCore™ Complex supercharges sirtuin activity, restoring the genetic instructions that drive cellular repair and youthful regeneration. This slows and reverses the aging process at the genetic level—restoring your skin to its youthful state.
Sirtuin activation is the foundation of youthful skin—but it doesn’t work alone. True rejuvenation requires a complete anti-aging powerhouse, where renewal, hydration, and repair work in synergy to maximize skin renewal and longevity. That’s why we created the TriCore™ Complex: a perfectly calibrated system where each element amplifies the next, creating the ideal environment for sustained cellular renewal and long-term skin health.
The Revolutionary TriCore™ Complex: 3 Cores to Transformed Skin
Cellular Renewal >> Sirtuin Power Boost >> Moisture Shield
CORE 1:
The Renewal Engine
Powered by:
0.1% Retinal
A powerful renewal system that works 11x faster than regular retinol, stimulating deep collagen synthesis and accelerating cellular turnover.
CORE 2:
Sirtuin Activation Complex
Powered by: Copper Peptide,
Matrixyl® 3000, Resveratrol
A precision-engineered power system that amplifies Retinal’s potency while activating sirtuin-driven genetic repair.
CORE 3:
Active Hydration Matrix
Powered by: Hyaluronic Acid,
Ceramides, Squalane, Glycerin
A precision-calibrated hydration system that creates the optimal environment for cellular renewal while strengthening the skin’s protective barrier.